Sinus Defense contains Transfer Factors, small, immune signaling peptides or proteins that have the unique effect of modulating the immune system, and select antigens, and nosodes. Basically, this unique and well-studied combination of ingredients are intended to "tell" the body to turn on the correct signals when it encounters disease-causing agents, and then to dampen the signals when the danger is eliminated or neutralized. In effect, Sinus Defense is designed to help body reclaim a proper, efficient, and protective immune response that will benefit and not send it into a tailspin when exposures occur. Customers and patients say that when they use Sinus Defense regularly, chronic infections and viruses, like HIV and herpes, seem to "teach" the body to elicit a better immune response, so that they have less inflammation and symptoms overall. Prolonged and repeated use also seens to induce quicker and better outcomes.

The ingredients in Sinus Defense are designed to act like antibodies, so its effects are often felt immediately and should assist the body in continuing to make antibodies. (For reference, immunotherapy takes 6-8 weeks to have the body make antibodies.) Sinus Defense contains multiple ingredients in one dose to a wide variety of pathogens, whereas allergy shots and immunotherapy are usually single antigen and require 6-8 weeks of use for the body to make the antibody. Because Sinus Defense is designed to harness cell-mediated immunity, the Transfer Factor molecules bind to the surface of the pathogen, tagging it for the macrophages (“big eaters”) to eliminate it. The idea is that by removing the pathogen quickly, the downstream symptoms do not occur, because the CAUSE of the inflammation is no longer present.

To help better describe the mechanism and thought process behind Sinus Defense, Dr. Donald Dennis, MD, FACS, explains how he created the homeopathic product and refined its ingredients over 20 years to help his own patients:

“In chronic sinusitis it was shown by the Mayo clinic study in 1999 that 93% of chronic sinusitis is caused by an immune reaction to mold that causes a reaction in the sinus mucosa. When the immune reaction occurs, eosinophils (white blood cells) migrate into the sinus mucosa, releasing major basic protein that causes cilia damage and microscopic pits in the sinus lining. The pits then trap mucous and the bacteria multiply and cause recurrent sinus infections. Many people with chronic sinusitis were not getting well, because they were not addressing fungus. They were also having viral activation to other pathogens and got sick easily when exposed to just about anything. I needed ingredients that would help the immune system do its job better and identify the mold quickly to remove it from the mucosa to prevent the reaction. We found that Transfer Factor removed enough fungus so that the white blood cells did not bind to it, and that the addition of certain nosodes markedly reduced overall inflammation. (But, the environmental air must also be addressed, because the volume of air you breathe each day exceeds 2,500 gallons!) The ingredients in Sinus Defense are designed to work well for all the antigens that mold patients battle--Lyme, Epstein Barr, strep, etc. This makes it effective for a multitude of people and for many common pathogens by just increasing the dose.”